An asymmetric normal-electron-demand aza-Diels-Alder reaction via trienamine catalysis.
نویسندگان
چکیده
An asymmetric normal-electron-demand aza-Diels-Alder cycloaddition of 2-aryl-3H-indol-3-ones and 2,4-dienals was explored via trienamine catalysis of a chiral secondary amine. Multifunctional tricyclic polyhydropyrido[1,2-a]indoles were efficiently constructed in good stereoselectivity (up to 92% ee, >19 : 1 dr).
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 47 شماره
صفحات -
تاریخ انتشار 2013